tag:blogger.com,1999:blog-8374717725359458448.post5192774808300810139..comments2014-04-21T20:03:08.168-07:00Comments on Biotech Marketer: Ion Torrent's Roadmap to the $500 GenomeAnonymoushttp://www.blogger.com/profile/08590569202982138251noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-8374717725359458448.post-56587274117166255412011-10-20T12:51:53.478-07:002011-10-20T12:51:53.478-07:00Anonymous #2,
It's now been 'a couple of ...Anonymous #2,<br /><br />It's now been 'a couple of months'. Has the 'serious competitor' emerged yet? Is it GnuBIO, ONP, someone else? Or do we need to wait a bit longer?Anonymoushttps://www.blogger.com/profile/08590569202982138251noreply@blogger.comtag:blogger.com,1999:blog-8374717725359458448.post-58255798570305500132011-08-18T04:20:56.233-07:002011-08-18T04:20:56.233-07:00Hi all
Just wait a couple of months and you will s...Hi all<br />Just wait a couple of months and you will see a serious competitor to this.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8374717725359458448.post-69449055422118079262011-08-17T09:08:41.027-07:002011-08-17T09:08:41.027-07:00Keith - one more point: the table already accounts...Keith - one more point: the table already accounts for the smaller bead sizes/increased density. So, by mid-2013, even if they're at their maximum stated density, they'll either need to be close to 100% fill efficiency or at read lengths greater than 1kb. Or, they'll have increased the density or increased the chip size. They just didn't talk about that possibility in the Nature paper.Anonymoushttps://www.blogger.com/profile/08590569202982138251noreply@blogger.comtag:blogger.com,1999:blog-8374717725359458448.post-52255887118536668782011-08-17T09:04:59.623-07:002011-08-17T09:04:59.623-07:00Keith, I agree with you completely. I didn't a...Keith, I agree with you completely. I didn't attempt to layout the exact upgrade path, but rather take a guess at what the performance might be at 6 month increments.<br /><br />The 100% fill efficiency is pretty unrealistic, but I was using those #s as a kind of shortcut. The real point is that it will have to be pretty high unless the read lengths will be significantly over 1kb.<br /><br />And, yes, everything occurs in too-large jumps. That's just me being lazy. Maybe I'll go back and try to smooth it out a bit.Anonymoushttps://www.blogger.com/profile/08590569202982138251noreply@blogger.comtag:blogger.com,1999:blog-8374717725359458448.post-38324245407943010622011-08-17T07:15:40.328-07:002011-08-17T07:15:40.328-07:00I'd really question whether either fill effici...I'd really question whether either fill efficiency or live beads can be gotten to 100%, and even if it approaches these I would expect more of a step-wise / asymptotic approach.<br /><br />Similarly, I will be surprised if the jumps in read length in the future are quite as large, particularly with smaller bead sizes to support higher densities. Perhaps they will get up to 1Kb, but I'm guessing it will be in smaller steps.Keith Robisonhttps://www.blogger.com/profile/04765318239070312590noreply@blogger.comtag:blogger.com,1999:blog-8374717725359458448.post-3033611514135452802011-08-15T14:25:15.701-07:002011-08-15T14:25:15.701-07:00You know this is irrelevant, cost of a genome coul...You know this is irrelevant, cost of a genome could be free today on a 10,000$ machine and it would drive Life Technologies directly to bankruptcy. The adoption will simply not follow this roadmap and if it did, clinical sequencing wouldn't be truly used routinely in 2013... You and I both know that dirty little secret.Anonymousnoreply@blogger.com